I've been using Alien Camel for a while to manage my personal email. Although not free (but you get what you pay for), Alien Camel is easily the best mail product I've used. Excellent spam & junk mail functionality, including white and black list address management, web client, POP3 and IMAP4 support, disposable email addresses, full backup and no ads. To quote Alien Camel - it's the last email you'll ever need. In case you were wondering, Alien Camel is an acronym for 'clean email'!
